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Updated: May 28, 2026

No. of Questions: 562 Questions & Answers with Testing Engine

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ASCP-MLT Practice Q&A's

ASCP-MLT PDF
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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. If your reactions are strong at immediate spin (3+) and then get weaker at AHG (w+), it could mean the presence of a strong cold antibody.
Cold antibodies tend to be IgM and their optimum phase for reactivity is immediate spin. Incubation and washing of the sample may cause the agglutination that occurred at room temperature to break down. This would appear as a weaker reaction at AHG.
If the reaction strengths varied in each panel cell then that could be an indication that there are multiple antibodies present.
Your screen cells are 3+ at immediate spin and weak (W)+ at AHG. Your auto control is negative for both phases. Some of your antibody panel cells are 3+ at immediate spin and negative at AHG. What should you suspect?

A) Bad specimen draw
B) A cold antibody may be present
C) A warm autoantibody is present


2. What is the CORRECT blood-to-anticoagulant ratio for coagulations tests?

A) 5:1
B) 10:1
C) 4:1
D) 9:1


3. Eosinophils do not have cytoplasm containing large purple/blue-staining granules. Instead, their granules are large but are orange/red in color. These granules are very distinctive for this type of cell, typically making their identification simple.
ll of the following statements describe an eosinophil EXCEPT:

A) Cytoplasm contains large purple/blue-staining granules.
B) Cytoplasm contains large reddish-orange granules.
C) May be called an "eo"
D) Is a member of the granulocyte series


4. The Western Blot Assay is used as a confirmatory test for which of the following:

A) Anti-HCV
B) CMV Antibody
C) Anti-HIV-1
D) HBsAg


5. Osteoblasts are generally seen in clusters while plasma cells are often more diffusely distributed. Osteoblasts have delicate cytoplasm, whereas plasma cells have dense basophilic cytoplasm with a perinuclear halo.
Hematology
The large cell shown in the illustration to the right is occasionally seen in the bone marrow and can be mistaken for a plasma cell - what is this cell called:

A) Osteoblast
B) Myeloblast
C) Megakaryoblast
D) Stem cell


Solutions:

Question # 1
Answer: B
Question # 2
Answer: D
Question # 3
Answer: A
Question # 4
Answer: A
Question # 5
Answer: A

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